If you’ve never made Mississippi Pot Roast, you’re in for a treat! This tender, flavorful roast is a Sunday Pot Roast dinner classic — and the best part? The leftovers make amazing Mississippi Pot Roast Sliders, tacos, and more, perfect for keeping dinner exciting all week long.
Prep Time15 minutesmins
Cook Time30 minutesmins
Mississippi Pot Roast Cook Time6 hourshrs
Servings: 6sliders
Author: Pam Werley
Ingredients
For Mississippi Pot Roast:
3poundsboneless chuck roast or top or bottom round roast
2teaspoonskosher saltplus more to taste
1½teaspoonsfreshly ground black pepperplus more to taste
¼cupall-purpose flour
3tablespoonscanola oil or any neutral oil
4tablespoonsunsalted butter
8 to 12pepperoncini
Homemade Ranch Dressing:
¼cupmayonnaise
2Tablespoonsapple cider vinegar
1 ½teaspoondried dill
¾teaspoonsweet paprika
½teaspoonfresh lemon juice
2teaspoonmilk
For the Sliders
6rollssquare soft white dinner
3tablespoonsranch dressing
¾cupleft-over Mississippi Pot Roastshredded
4ouncesdeli Provolone or Pepper Jack cheese6 thin slices
4 to 6pepperoncinichopped
Pepper
2tablespoonsunsalted butter
1tablespoonsau jus gravyreserved pot roast cooking liquid
Instructions
Slow Cook the Mississippi Pot Roast:
Place roast on a cutting board and rub the salt and pepper all over it. Sprinkle the flour all over the seasoned meat and massage it into the flesh. Heat the oil in a large sauté pan set over high heat until it is shimmering and about to smoke. Place the roast in the pan and brown on all sides, 4 to 5 minutes a side, to create a crust. Remove roast from pan and place it in the bowl of a slow cooker. Add the butter and the pepperoncini to the meat. Put the lid on the slow cooker, and set the machine to low for 6 to 8 hours.
Make Ranch Dressing
As the roast heats, make a ranch dressing. Combine the mayonnaise, vinegar, dill and paprika in a small bowl and whisk to emulsify. Whisk in lemon juice and milk. Place 3 Tablespoons of ranch dressing in a small bowl , cover and refrigerate until ready to make sliders. Remove the lid from the slow cooker and add the remaining dressing. Replace the top and allow to continue cooking, undisturbed, for 6 to 8 hours, or until you can shred the meat easily using 2 forks. Mix the meat with the gravy surrounding it.
Assemble the Sliders:
Adjust your oven rack to the middle position and preheat your oven to 350°F. Slice rolls in half horizontally, keeping the tops and bottoms connected if you can. Take about 2 tablespoons of reserved ranch dressing and spread it across the cut sides of both the roll tops and bottoms.
Place the bottoms of your rolls, cut side up, in an 8x8-inch baking dish. Take 2 to 3 tablespoons of pot roast and pile it onto each roll bottom. Fold each cheese slice in thirds, and then fold it once more in half so it creates a thick little stack of cheese. Place one stack over each pile of pot roast.
Next, add chopped pepperoncini and place on top of the cheese. If you love a little tangy heat, you could even do more — your call! Sprinkle on a little black pepper if you like, then cap each slider with the top halves of your rolls.
In a small microwave-safe bowl, melt 2 tablespoons of butter, about 30 seconds in the microwave. Whisk in 1 tablespoon of reserved au jus from your pot roast and 1 tablespoon of ranch dressing. This buttery mixture is pure gold — it’s going to soak into the buns and make them ridiculously flavorful.
Using a pastry brush (or even just a spoon) and generously brush all over the tops and edges of your sliders with that buttery sauce. Cover your baking dish tightly with aluminum foil and let the sliders sit for 10 minutes. Pop them into your preheated oven and bake for 20 minutes. Uncover them and keep baking for another 7 to 9 minutes, just until the cheese is beautifully melted and the tops feel slightly firm to the touch. Let the sliders cool for about 10 minutes before serving.
Notes
Bonus Tip: If you want to make these sliders ahead of time, you totally can! Just assemble them, brush them with the sauce, cover them tightly, and refrigerate them for up to 1 day in advance. When you’re ready to bake, bring them to room temperature for about 30 minutes, then pop them in the oven as directed. Perfect for easy entertaining!